Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.62 |
| ▸ | TSHR | P16473 | 1/20 | 0.62 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | HTR1A | P08908 | 4/20 | 0.44 |
| ▸ | HTR7 | P34969 | 4/20 | 0.44 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.44 |
| ▸ | PTGES | O14684 | 1/20 | 0.44 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.44 |
| ▸ | PPARA | Q07869 | 1/20 | 0.44 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.41 |
| ▸ | RECQL | P46063 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16959543 | 0.86 | KDM4E (0.48) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5018851 | 0.84 | KDM4E (0.69) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL4854291 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL5725601 | 0.82 | KDM4E (0.67) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12652785 | 0.82 | KDM4E (0.67) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL12417824 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL10224193 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL6480911 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL18353918 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 | |
| SCHEMBL7638337 | 0.82 | KDM4E (0.62) | KDM4ETSHRALDH1A1LMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1817282-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | AstraZeneca AB (SE) | 2007-08-15 | — | — | EP | disclosed |
| WO-2006056752-A1 | PHENOXYACETIC ACID DERIVATIVES USEFUL FOR TREATING RESPIRATORY DISEASES | ASTRAZENECA AB (SE) | 2006-06-01 | — | — | WO | disclosed |