Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK14 | Q16539 | 12/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 3/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 2/20 | 0.36 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.36 |
| ▸ | PLK1 | P53350 | 2/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5204817 | 0.90 | MAPK14 (0.45) | MAPK14MAPK11SCN9A | |
| SCHEMBL5205934 | 0.90 | MAPK14 (0.46) | MAPK14MAPK11 | |
| SCHEMBL5205668 | 0.89 | MAPK14 (0.47) | MAPK14MAPK11 | |
| SCHEMBL5201926 | 0.85 | MAPK14 (0.43) | MAPK14MAPK11 | |
| Trifluoroacetic Acid SCHEMBL5203957 | 0.83 | MAPK14 (0.43) | MAPK14MAPK11MAPKAPK2 | |
| SCHEMBL5206786 | 0.83 | MAPK14 (0.43) | MAPK14MAPK11 | |
| SCHEMBL5204463 | 0.83 | MAPK14 (0.47) | MAPK14MAPK11 | |
| SCHEMBL5202280 | 0.83 | MAPK14 (0.44) | MAPK14MAPK11MAPKAPK2 | |
| SCHEMBL5201921 | 0.82 | MAPK14 (0.41) | MAPK14MAPK11MAPKAPK2 | |
| SCHEMBL5206024 | 0.80 | MAPK14 (0.46) | MAPK14MAPK11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802590-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | Pharmacia & Upjohn Company LLC (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006040666-A1 | SUBSTITUTED N-ALKYLPYRIMIDINONES | PHARMACIA & UPJOHN COMPANY LLC (US) | 2006-04-20 | — | — | WO | disclosed |