Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201473 | 0.91 | MEN1 (0.54) | MEN1KMT2ACHRM2 | |
| SCHEMBL5202501 | 0.85 | MEN1 (0.58) | MEN1KMT2ACHRM2 | |
| SCHEMBL14571605 | 0.85 | MEN1 (0.58) | MEN1KMT2A | |
| SCHEMBL20883161 | 0.83 | MEN1 (0.44) | MEN1KMT2ACHRM2 | |
| SCHEMBL5201772 | 0.83 | MEN1 (0.57) | MEN1KMT2A | |
| SCHEMBL20883160 | 0.81 | MEN1 (0.63) | MEN1KMT2ACHRM2 | |
| SCHEMBL5235926 | 0.81 | MAPK14 (0.69) | MAPK14 | |
| SCHEMBL5203675 | 0.81 | MEN1 (0.63) | MEN1KMT2A | |
| SCHEMBL5353806 | 0.80 | MEN1 (0.60) | MEN1KMT2ACHRM2MAPK14 | |
| SCHEMBL14444879 | 0.80 | MAPK14 (0.58) | MAPK14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1178983-B1 | INDOLE-TYPE DERIVATIVES AS INHIBITORS OF P38 KINASE | SCIOS INC (US) | 2007-10-24 | — | — | EP | claimed |