SCHEMBL5203260

SCHEMBL5203260

CC(C)(CC(=O)O)SN=O

nearest known ligand 0.46

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
HMGCR P04035 1/20 0.44
CHRM1 P11229 1/20 0.44
TBXA2R P21731 1/20 0.44
ADRA1A P35348 1/20 0.44
CYP2C19 P33261 3/20 0.42
HIF1A Q16665 2/20 0.42
CYP2D6 P10635 2/20 0.42
TSHR P16473 1/20 0.42
KDM4E B2RXH2 1/20 0.38
FFAR1 O14842 1/20 0.38
CPT2 P23786 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
ALDH1A1 P00352 1/20 0.33
BHMT Q93088 3/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5675851 0.74 GAA (0.35) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL6536931 0.74 HMGCR (0.52) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL289826 0.72
SCHEMBL7301614 0.72
SCHEMBL7252624 0.70 HMGCR (0.61) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL23534046 0.68
SCHEMBL20425149 0.68 HMGCR (0.46) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL20220523 0.67 HMGCR (0.44) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL11496709 0.65 TSHR (0.46) HMGCRCHRM1TBXA2RADRA1ACYP2C19
SCHEMBL48109 0.64 KDM4E (0.65) HMGCRCHRM1TBXA2RADRA1ACYP2C19

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1018879-B1 NITROSATED AND NITROSYLATED ALPHA-ADRENERGIC RECEPTOR ANTAGONIST COMPOUNDS, COMPOSITIONS AND THEIR USES NITROMED INC (US) 2007-08-01 EP claimed
WO-2020067485-A1 INDUCER OF CARDIAC ABILITY TO SYNTHESIZE ACETYLCHOLINE 学校法人日本医科大学 2020-04-02 WO disclosed
WO-2009003624-A1 HYALURONIC ACID DERIVATIVES CONTAINING GROUPS ABLE TO RELEASE NO FIDIA FARMACEUTICI S.P.A. (IT) 2009-01-08 WO disclosed
EP-1603933-A2 NITROSATED AND NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE Nitromed, Inc. (US) 2005-12-14 EP disclosed
WO-2004098538-A2 NITROSATED AND NITROSYLATED COMPOUNDS, COMPOSITIONS AND METHODS OF USE NITROMED, INC. (US) 2004-11-18 WO disclosed