Fluoride

Fluoride

SCHEMBL5203462

CC(C)CC(=O)CC(C)C.F

nearest known ligand 0.56

Full drug profile on Sugi Atlas →

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 2/20 0.56
ALDH1A1 P00352 1/20 0.56
TDP1 Q9NUW8 1/20 0.56
CA2 P00918 1/20 0.50
ACHE P22303 1/20 0.48
SMN1; SMN2 Q16637 1/20 0.37
MMP1 P03956 1/20 0.37
MMP2 P08253 1/20 0.37
MMP3 P08254 1/20 0.37
MMP9 P14780 1/20 0.37
MMP13 P45452 1/20 0.37
FFAR1 O14842 1/20 0.36
TSHR P16473 1/20 0.35
CYP2D6 P10635 1/20 0.35
CA1 P00915 1/20 0.35
PTPN1 P18031 1/20 0.34
RNPEP Q9H4A4 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10834211 0.96 CYP2C19 (0.59) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL36990 0.96 CYP2C19 (0.59) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL29243915 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
Water SCHEMBL3865217 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL8720706 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
Hydrogen Peroxide SCHEMBL16799548 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
SCHEMBL9659709 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
Ammonia Solution, Strong SCHEMBL7923599 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
Methane SCHEMBL9155165 0.93 CYP2C19 (0.56) CYP2C19ALDH1A1TDP1CA2ACHE
Formaldehyde SCHEMBL11857202 0.90 CYP2C19 (0.54) CYP2C19ALDH1A1TDP1CA2ACHE

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1375469-B1 A process for preparing acylfluorides SOLVAY SOLEXIS SPA (IT) 2007-08-22 EP disclosed
US-6998506-B2 Process for preparing acylfluorides SOLVAY SOLEXIS SPA (IT) 2006-02-14 US disclosed
US-20050080291-A1 Process for preparing acylfluorides SOLVAY SOLEXIS S.P.A. 2005-04-14 US disclosed
US-6852884-B2 Process for preparing acylfluorides SOLVAY SOLEXIS S.P.A. (IT) 2005-02-08 US disclosed
EP-1375469-A1 A process for preparing acylfluorides Solvay Solexis S.p.A. (IT) 2004-01-02 EP disclosed
US-20030236436-A1 Process for preparing acylfluorides SOLVAY SOLEXIS S.P.A. 2003-12-25 US disclosed