Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGAL | P20701 | 20/20 | 1.00 |
| ▸ | ITGB2 | P05107 | 19/20 | 1.00 |
| ▸ | ICAM1 | P05362 | 19/20 | 1.00 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5203590 | 1.00 | ITGAL (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL5203942 | 0.89 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL5239341 | 0.89 | ITGAL (0.80) | ITGALITGB2ICAM1 | |
| SCHEMBL13879396 | 0.84 | ITGAL (0.73) | ITGALITGB2ICAM1 | |
| SCHEMBL12647778 | 0.83 | ITGAL (0.70) | ITGALITGB2ICAM1 | |
| SCHEMBL6312522 | 0.83 | ITGAL (0.70) | ITGALITGB2ICAM1 | |
| SCHEMBL21688324 | 0.82 | ITGAL (0.69) | ITGALITGB2ICAM1 | |
| SCHEMBL13817247 | 0.77 | ITGB2 (1.00) | ITGALITGB2ICAM1 | |
| SCHEMBL13817048 | 0.77 | ITGB2 (0.71) | ITGALITGB2ICAM1 | |
| SCHEMBL4018223 | 0.77 | ITGB2 (1.00) | ITGALITGB2ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 15 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1284973-B1 | INHIBITORS OF ALPHA L BETA 2 MEDIATED CELL ADHESION | TANABE SEIYAKU CO (JP) | 2007-06-27 | — | — | EP | disclosed |
| EP-1311852-A4 | METHODS AND MOLECULES USEFUL FOR IDENTIFYING MOLECULES THAT BIND LFA-1 AND FOR DETERMINING RECEPTOR OCCUPANCY | BOEHRINGER INGELHEIM PHARMA (US) | 2006-03-15 | — | — | EP | disclosed |
| US-20050222193-A1 | Novel combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-10-06 | — | — | US | disclosed |
| WO-2005074932-A1 | THE USE OF (S) - PANTOPRAZOLE MAGNESIUM FOR THE TREATMENT OF AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2005-08-18 | — | — | WO | disclosed |
| US-20050165041-A1 | Combination for the treatment of airway disorders | ALTANA PHARMA AG (DE) | 2005-07-28 | — | — | US | disclosed |
| EP-1517706-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA Pharma AG (DE) | 2005-03-30 | — | — | EP | disclosed |
| EP-1506016-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA Pharma AG (DE) | 2005-02-16 | — | — | EP | disclosed |
| US-6846643-B2 | Methods and molecules useful for identifying molecules that bind LFA-1 and for determining receptor occupancy | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2005-01-25 | — | — | US | disclosed |
| WO-2003094967-A2 | NEW COMBINATION OF REVERSIBLE PROTON PUMP INHIBITORS AND AIRWAY THERAPEUTICS FOR TREATING AIRWAY DISORDERS | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| WO-2003094968-A2 | COMBINATION OF A PROTON PUMP INHIBITOR AND A RESPIRATORY AGENT FOR THE TREATMENT OF RESPIRATORY DISEASES | ALTANA PHARMA AG (DE) | 2003-11-20 | — | — | WO | disclosed |
| US-20030175814-A1 | Methods and molecules useful for identifying molecules that bind LFA-1 and for determining receptor occupancy | WOSKA JOSEPH R (US) | 2003-09-18 | — | — | US | disclosed |
| EP-1311852-A1 | METHODS AND MOLECULES USEFUL FOR IDENTIFYING MOLECULES THAT BIND LFA-1 AND FOR DETERMINING RECEPTOR OCCUPANCY | BOEHRINGER INGELHEIM PHARMACEUTICALS INC. (US) | 2003-05-21 | — | — | EP | disclosed |
| US-20020068305-A1 | Methods and molecules useful for identifying molecules that bind LFA-1 and for determining receptor occupancy | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. | 2002-06-06 | — | — | US | disclosed |
| WO-2002024307-A2 | REDUCING THE CONTENT OF PARTICULAR CELL TYPES IN A BIOLOGICAL SAMPLE | ALLIED THERAPEUTICS LIMITED (GB) | 2002-03-28 | — | — | WO | disclosed |
| WO-2002014865-A1 | METHODS AND MOLECULES USEFUL FOR IDENTIFYING MOLECULES THAT BIND LFA-1 AND FOR DETERMINING RECEPTOR OCCUPANCY | BOEHRINGER INGELHEIM PHARMACEUTICALS, INC. (US) | 2002-02-21 | — | — | WO | disclosed |