Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA14 | Q9ULX7 | 4/20 | 0.39 |
| ▸ | CA12 | O43570 | 2/20 | 0.39 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
| ▸ | CASP7 | P55210 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 2/20 | 0.32 |
| ▸ | CA2 | P00918 | 2/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.30 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.30 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.30 |
| ▸ | POLB | P06746 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18796420 | 0.81 | CA14 (0.41) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL646682 | 0.81 | MEN1 (0.33) | CA14CA1CA2CA7HDAC1 | |
| SCHEMBL9455522 | 0.81 | CA14 (0.41) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL7021061 | 0.81 | CA14 (0.41) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL19492022 | 0.80 | USP30 (0.35) | CA14CA12DGAT1CA1CA2 | |
| SCHEMBL3724110 | 0.78 | CA14 (0.39) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9797673 | 0.78 | CA14 (0.39) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL9797670 | 0.78 | CA14 (0.39) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL3724107 | 0.78 | CA14 (0.39) | CA14CA12DGAT1SMN1; SMN2ALDH1A1 | |
| SCHEMBL23805207 | 0.77 | CA14 (0.34) | CA14CA12DGAT1CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1809657-A1 | CYCLIC NONAPEPTIDE AMIDES | AiCuris GmbH & Co. KG (DE) | 2007-07-25 | — | — | EP | disclosed |
| WO-2006048156-A1 | CYCLIC NONAPEPTIDE AMIDES | AICURIS GMBH & CO. KG (DE) | 2006-05-11 | — | — | WO | disclosed |