Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F10 | P00742 | 18/20 | 0.62 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.52 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5201605 | 0.95 | F10 (0.55) | F10KCNH2MEN1MAPTTSHR | |
| SCHEMBL5208090 | 0.95 | F10 (0.55) | F10KCNH2MEN1MAPTTSHR | |
| SCHEMBL5208578 | 0.94 | F10 (0.54) | F10KCNH2MEN1MAPTTSHR | |
| SCHEMBL5394554 | 0.92 | F10 (0.73) | F10KCNH2 | |
| SCHEMBL5205339 | 0.90 | F10 (0.55) | F10KCNH2 | |
| SCHEMBL5204938 | 0.89 | F10 (0.54) | F10KCNH2 | |
| SCHEMBL5369020 | 0.89 | MAPT (0.51) | F10MEN1MAPTTSHRKMT2A | |
| SCHEMBL5204970 | 0.88 | MAPT (0.48) | F10MEN1MAPTTSHRKMT2A | |
| SCHEMBL4858776 | 0.86 | F10 (0.51) | F10KCNH2MEN1MAPTTSHR | |
| SCHEMBL5392795 | 0.86 | F10 (0.65) | F10KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307444-B1 | SUBSTITUTED HETEROCYCLIC AMIDES | LILLY CO ELI (US) | 2007-10-03 | — | — | EP | disclosed |
| US-7160878-B2 | Substituted heterocyclic amides | ELI LILLY AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160878-B2 | Substituted heterocyclic amides | ELI LILLY AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |
| US-7160878-B2 | Substituted heterocyclic amides | ELI LILLY AND COMPANY (US) | 2007-01-09 | — | — | US | disclosed |