Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1971245 | 0.83 | — | — | |
| SCHEMBL2029980 | 0.79 | CYP2C19 (0.37) | CYP2C19ALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL23925603 | 0.78 | — | — | |
| SCHEMBL17223871 | 0.78 | CYP2C19 (0.56) | CYP2C19ALDH1A1CYP4F2CYP4A11 | |
| SCHEMBL5546369 | 0.77 | CYP2C19 (0.35) | CYP2C19ALDH1A1HSD17B10 | |
| SCHEMBL27504849 | 0.77 | CYP2C19 (0.35) | CYP2C19ALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL6639755 | 0.77 | MME (0.37) | CYP2C19ALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL18095993 | 0.77 | CYP2C19 (0.61) | CYP2C19ALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL1971456 | 0.77 | CYP2C19 (0.35) | CYP2C19ALDH1A1CYP4F2CYP4A11HSD17B10 | |
| SCHEMBL14049433 | 0.76 | CYP2C19 (0.60) | CYP2C19ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1758891-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | Pfizer Japan Inc. (JP) | 2007-03-07 | — | — | EP | disclosed |
| WO-2005123718-A2 | BENZIMIDAZOLONE CARBOXYLIC ACID DERIVATIVES | PFIZER JAPAN INC. (JP) | 2005-12-29 | — | — | WO | disclosed |
| CN-1177821-C | Matrix metalloprotease inhibitors | - | 2004-12-01 | — | — | CN | disclosed |
| EP-1282614-B1 | HYDROXAMIC ACID DERIVATIVES | DARWIN DISCOVERY LTD (GB) | 2003-11-12 | — | — | EP | disclosed |
| CN-1160045-A | Matrix metalloprotease inhibitors | HOFFMANN LA ROCHE (CH) | 1997-09-24 | — | — | CN | disclosed |