⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10838929 | 0.78 | — | — | |
| SCHEMBL48217 | 0.73 | — | — | |
| SCHEMBL9736289 | 0.72 | — | — | |
| SCHEMBL875900 | 0.70 | KDM4E (0.42) | — | |
| Hydrochloric Acid SCHEMBL8888872 | 0.70 | — | — | |
| SCHEMBL9186647 | 0.70 | KDM4E (0.42) | — | |
| SCHEMBL28140994 | 0.67 | — | — | |
| SCHEMBL13259691 | 0.67 | — | — | |
| SCHEMBL14951930 | 0.67 | — | — | |
| SCHEMBL15870062 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1597235-B1 | NON-NUCLEOSIDE REVERSE TRANSCRIPTASE INHIBITORS | HOFFMANN LA ROCHE (CH) | 2007-08-15 | — | — | EP | disclosed |
| US-7241794-B2 | Nonnucleoside reverse transcriptase inhibitors | ROCHEPALO ALTO LLC (US) | 2007-07-10 | — | — | US | disclosed |
| EP-1175213-A4 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL MYERS SQUIBB CO (US) | 2007-04-11 | — | — | EP | disclosed |
| US-7053110-B2 | Heterocyclic aromatic compounds useful as growth hormone secreagogues | BRISTOL-MYERS SQUIBB COMPANY (US) | 2006-05-30 | — | — | US | disclosed |
| US-6969727-B2 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-11-29 | — | — | US | disclosed |
| US-6908938-B2 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | BRISTOL-MYERS SQUIBB COMPANY (US) | 2005-06-21 | — | — | US | disclosed |
| US-20040192666-A1 | Nonnucleoside reverse transcriptase inhibitors | ROCHE PALO ALTO LLC | 2004-09-30 | — | — | US | disclosed |
| US-20040072881-A1 | Heterocyclic aromatic compounds useful as growth hormone secreagogues | ROBL JEFFREY A (US) | 2004-04-15 | — | — | US | disclosed |
| US-20040029935-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | ROBL JEFFREY A (US) | 2004-02-12 | — | — | US | disclosed |
| US-20040002525-A1 | Heterocyclic aromatic compounds useful as growth hormone secretagogues | A ROBL JEFFREY (US) | 2004-01-01 | — | — | US | disclosed |
| US-6660760-B1 | Treating obesity, osteoporosis | BRISTOL-MYERS SQUIBB CO. | 2003-12-09 | — | — | US | disclosed |
| US-6525203-B1 | Treating obesity, osteoporosis by improving bone density and stimulating increase in muscle mass and strength | BRISTOL-MYERS SQUIBB COMPANY | 2003-02-25 | — | — | US | disclosed |
| US-6518292-B1 | Stimulating endogenous production or release of growth hormone and in treating obesity, osteoporosis (improving bone density) and in improving muscle mass and muscle strength | BRISTOL-MYERS SQUIBB CO. | 2003-02-11 | — | — | US | disclosed |
| EP-1175213-A2 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-01-30 | — | — | EP | disclosed |
| WO-2000054729-A2 | HETEROCYCLIC AROMATIC COMPOUNDS USEFUL AS GROWTH HORMONE SECRETAGOGUES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2000-09-21 | — | — | WO | disclosed |
| US-4045209-A | Substituted ureas as herbicides | ROUSSEL UCLAF (FR) | 1977-08-30 | — | — | US | disclosed |