Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 20/20 | 0.63 |
| ▸ | CYP3A4 | P08684 | 5/20 | 0.63 |
| ▸ | CYP2C9 | P11712 | 7/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14498362 | 0.92 | ELANE (0.76) | ELANECYP3A4CYP2C9 | |
| SCHEMBL5204916 | 0.86 | ELANE (0.77) | ELANECYP3A4CYP2C9 | |
| SCHEMBL5623594 | 0.85 | ELANE (0.69) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8342560 | 0.85 | ELANE (0.52) | ELANECYP3A4CYP2C9 | |
| SCHEMBL8344736 | 0.84 | ELANE (0.76) | ELANECYP3A4CYP2C9 | |
| SCHEMBL2896316 | 0.84 | ELANE (0.76) | ELANECYP3A4CYP2C9 | |
| SCHEMBL333331 | 0.84 | ELANE (0.79) | ELANECYP3A4CYP2C9 | |
| SCHEMBL14431514 | 0.83 | ELANE (0.75) | ELANECYP3A4CYP2C9 | |
| SCHEMBL4681596 | 0.83 | ELANE (0.65) | ELANECYP3A4CYP2C9 | |
| SCHEMBL4684604 | 0.83 | ELANE (0.65) | ELANECYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1554246-B1 | DIHYDROPYRIDINONE DERIVATIVES AS HNE INHIBITORS | BAYER HEALTHCARE AG (DE) | 2007-08-22 | — | — | EP | disclosed |