SCHEMBL5207738

SCHEMBL5207738

CCc1c(NC(=O)Nc2cccc3c2CC(O)CC3)cccc1C(=O)O

nearest known ligand 0.53

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
TRPV1 Q8NER1 19/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13613616 0.81 TRPV1 (0.56) TRPV1
SCHEMBL13613593 0.81 TRPV1 (0.52) TRPV1
SCHEMBL1573444 0.80 TRPV1 (0.60) TRPV1
SCHEMBL4377235 0.80 TRPV1 (0.60) TRPV1
SCHEMBL4336612 0.80 TRPV1 (0.64) TRPV1
SCHEMBL1716188 0.80 CCR3 (0.37) TRPV1
SCHEMBL13613713 0.79 TRPV1 (0.60) TRPV1
SCHEMBL13613696 0.79 TRPV1 (0.59) TRPV1
SCHEMBL14278338 0.78 TRPV1 (0.53) TRPV1
SCHEMBL14278339 0.77 TRPV1 (0.53) TRPV1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1506167-B1 HYDROXY TETRAHYDRO-NAPHTHALENYLUREA DERIVATIVES BAYER HEALTHCARE AG (DE) 2007-08-29 EP claimed