Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.49 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.49 |
| ▸ | CACNA1B | Q00975 | 1/20 | 0.49 |
| ▸ | APBA1 | Q02410 | 1/20 | 0.49 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | MAOA | P21397 | 1/20 | 0.49 |
| ▸ | FDFT1 | P37268 | 1/20 | 0.48 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.48 |
| ▸ | USP2 | O75604 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6139722 | 0.99 | HTT (0.50) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL8207095 | 0.88 | HTT (0.52) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL378149 | 0.86 | HPGD (0.54) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL24754432 | 0.85 | HTT (0.50) | HTTHPGDMEN1KMT2AALDH1A1 | |
| Hydrochloric Acid SCHEMBL6139554 | 0.85 | HPGD (0.52) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL3457437 | 0.85 | HPGD (0.55) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL378276 | 0.85 | TDP1 (0.60) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL22015905 | 0.84 | HPGD (0.65) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL20188098 | 0.84 | HPGD (0.65) | HTTHPGDMEN1KMT2AALDH1A1 | |
| SCHEMBL23582930 | 0.84 | HTT (0.55) | HTTHPGDMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242083-B1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI AVENTIS (FR) | 2007-03-14 | — | — | EP | disclosed |
| EP-1242083-A1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Sanofi-Aventis (FR) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001043744-A1 | PHENOXYPROPANOLAMINES, METHOD FOR PRODUCING THEM AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | SANOFI-SYNTHELABO (FR) | 2001-06-21 | — | — | WO | disclosed |