Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 14/20 | 0.49 |
| ▸ | PARP1 | P09874 | 1/20 | 0.44 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5211024 | 0.92 | HRH3 (0.43) | HRH3HRH1 | |
| SCHEMBL4034857 | 0.88 | HRH3 (0.48) | HRH3PARP1HRH1 | |
| SCHEMBL5211294 | 0.88 | HRH3 (0.50) | HRH3PARP1HRH1 | |
| SCHEMBL5213075 | 0.87 | HRH3 (0.46) | HRH3PARP1HRH1 | |
| SCHEMBL5212822 | 0.85 | ACKR3 (0.46) | HRH3 | |
| SCHEMBL5283558 | 0.85 | HRH3 (0.54) | HRH3 | |
| SCHEMBL5213489 | 0.84 | HRH3 (0.57) | HRH3PARP1 | |
| SCHEMBL5212146 | 0.84 | HRH3 (0.54) | HRH3PARP1 | |
| Hydrochloric Acid SCHEMBL5210651 | 0.82 | HRH3 (0.48) | HRH3 | |
| Hydrochloric Acid SCHEMBL5213349 | 0.81 | HRH3 (0.47) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |