SCHEMBL5210696

SCHEMBL5210696

Cc1oc(-c2ccccc2)nc1CCOc1ccc(S(=O)(=O)N2CCC[C@H]2OC(=O)O)cc1Cl

nearest known ligand 0.51

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PPARG P37231 19/20 0.51
PPARA Q07869 16/20 0.51

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5210918 0.93 PPARG (0.43) PPARGPPARA
SCHEMBL5210578 0.91 PPARG (0.46) PPARGPPARA
SCHEMBL2521083 0.91 PPARG (0.54) PPARGPPARA
SCHEMBL2521085 0.91 PPARG (0.54) PPARGPPARA
SCHEMBL5211136 0.87 PPARG (0.56) PPARGPPARA
SCHEMBL2514703 0.84 PPARG (0.46) PPARGPPARA
SCHEMBL2514702 0.84 PPARG (0.46) PPARGPPARA
SCHEMBL5211025 0.84 PPARG (0.43) PPARGPPARA
SCHEMBL5310384 0.84 PPARG (0.48) PPARGPPARA
SCHEMBL5206107 0.84 PPARG (0.44) PPARGPPARA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1448523-B1 HETEROCYCLIC COMPOUNDS AND METHODS OF USE NOVARTIS AG (CH) 2007-08-22 EP claimed