Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 19/20 | 0.57 |
| ▸ | HRH1 | P35367 | 1/20 | 0.39 |
| ▸ | CDK1 | P06493 | 1/20 | 0.39 |
| ▸ | CDK2 | P24941 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL5210768 | 0.99 | HRH3 (0.56) | HRH3HRH1CDK1CDK2 | |
| SCHEMBL5210105 | 0.88 | HRH3 (0.60) | HRH3HRH1 | |
| SCHEMBL5212817 | 0.86 | HRH3 (0.61) | HRH3 | |
| SCHEMBL14431499 | 0.85 | HRH3 (0.75) | HRH3 | |
| SCHEMBL5212438 | 0.85 | HRH3 (0.60) | HRH3HRH1 | |
| Hydrochloric Acid SCHEMBL5211935 | 0.84 | HRH3 (0.59) | HRH3HRH1 | |
| SCHEMBL5210318 | 0.84 | HRH3 (0.59) | HRH3 | |
| SCHEMBL5210077 | 0.83 | HRH3 (0.58) | HRH3 | |
| SCHEMBL5210664 | 0.83 | HRH3 (0.61) | HRH3HRH1 | |
| SCHEMBL5209775 | 0.83 | HRH3 (0.53) | HRH3HRH1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1646620-B1 | SUBSTITUTED PIPERIDINES AS HISTAMINE H3 RECEPTOR LIGANDS | GLAXO GROUP LTD (GB) | 2007-08-15 | — | — | EP | claimed |