Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 0.77 |
| ▸ | CYP2C9 | P11712 | 5/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.64 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.64 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.64 |
| ▸ | CNR1 | P21554 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 3/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5213298 | 0.91 | CNR2 (0.74) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5216574 | 0.91 | CNR2 (0.74) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5079723 | 0.87 | CNR2 (1.00) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5214727 | 0.86 | CNR2 (0.73) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5215691 | 0.86 | CNR2 (0.85) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL4931804 | 0.86 | CNR2 (0.76) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5216776 | 0.85 | CNR2 (1.00) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5219165 | 0.84 | CNR2 (0.72) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5219032 | 0.84 | CNR2 (0.82) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 | |
| SCHEMBL5213612 | 0.84 | CNR2 (0.77) | CNR2CYP2C9CYP1A2CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | claimed |
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | disclosed |