Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4A | P27815 | 14/20 | 0.51 |
| ▸ | PDE4B | Q07343 | 15/20 | 0.50 |
| ▸ | PDE4C | Q08493 | 9/20 | 0.50 |
| ▸ | PDE4D | Q08499 | 9/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3541867 | 1.00 | PDE4A (0.51) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5807740 | 0.86 | PDE4A (0.53) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4462030 | 0.86 | PDE4A (0.49) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5762460 | 0.85 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5760783 | 0.85 | PDE4A (0.55) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL4466548 | 0.84 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5255366 | 0.83 | PDE4A (0.54) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3551154 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL5194511 | 0.82 | PDE4A (0.48) | PDE4APDE4BPDE4CPDE4D | |
| SCHEMBL3539215 | 0.82 | PDE4A (0.47) | PDE4APDE4BPDE4CPDE4D |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1802615-A1 | PHOSPHODIESTERASE 4 INHIBITORS | Memory Pharmaceuticals Corporation (US) | 2007-07-04 | — | — | EP | disclosed |
| WO-2006044955-A1 | PHOSPHODIESTERASE 4 INHIBITORS | MEMORY PHARMACEUTICALS CORPORATION (US) | 2006-04-27 | — | — | WO | disclosed |