SCHEMBL52154

SCHEMBL52154

CCCCC(CC)COC(=O)C(C)Br

nearest known ligand 0.64

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 5/20 0.64
TSHR P16473 3/20 0.64
TDP1 Q9NUW8 3/20 0.64
ATM Q13315 1/20 0.64
RECQL P46063 1/20 0.56
ALDH1A1 P00352 7/20 0.55
CA2 P00918 4/20 0.55
LMNA P02545 3/20 0.50
L3MBTL1 Q9Y468 1/20 0.50
MAPK1 P28482 3/20 0.49
HSD17B10 Q99714 1/20 0.49
PRSS1 P07477 1/20 0.49
PRSS2 P07478 1/20 0.49
PRSS3 P35030 1/20 0.49
MMP9 P14780 1/20 0.43
MMP8 P22894 1/20 0.43
MMP14 P50281 1/20 0.43
CA1 P00915 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9435917 1.00 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL9435931 1.00 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL29201907 0.87 ZDHHC7 (0.51) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL245036 0.87 CYP3A4 (0.66) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL7218980 0.85 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL15437967 0.85 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL358454 0.85 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL21052460 0.85 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL1108109 0.85 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL
SCHEMBL5198333 0.85 CYP3A4 (0.64) CYP3A4TSHRTDP1ATMRECQL

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 63 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250019560-A1 ACRYLIC MATERIALS AND USES THEREOF PPG INDUSTRIES OHIO, INC. (US) 2025-01-16 US disclosed
EP-4437053-A1 ACRYLIC MATERIALS AND USES THEREOF PPG Industries Ohio Inc. (US) 2024-10-02 EP disclosed
EP-4357422-A2 BLACK PIGMENTS COMPRISING GRAPHENIC CARBON PARTICLES PPG Industries Ohio, Inc. (US) 2024-04-24 EP disclosed
EP-3212717-B1 BLACK PIGMENTS COMPRISING GRAPHENIC CARBON PARTICLES PPG IND OHIO INC (US) 2024-04-17 EP disclosed
US-11958802-B2 Migration-resistant photopolymerization sensitizer KAWASAKI KASEI CHEMICALS LTD. (JP) 2024-04-16 US disclosed
CN-113166036-B Photopolymerizing sensitizers with migration resistance 川崎化成工业株式会社 2023-10-10 CN disclosed
WO-2023091979-A1 ACRYLIC MATERIALS AND USES THEREOF PPG INDUSTRIES OHIO, INC. (US) 2023-05-25 WO disclosed
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER KAWASAKI KASEI CHEMICALS LTD. (JP) 2022-04-07 US disclosed
EP-3974478-A2 SOLAR REFLECTIVE COATINGS AND COATING SYSTEMS PPG Industries Ohio, Inc. (US) 2022-03-30 EP disclosed
EP-2493988-B1 SOLAR REFLECTIVE COATINGS AND COATING SYSTEMS PPG IND OHIO INC (US) 2021-12-08 EP disclosed
US-20030032716-A1 Pigment dispersions containing dispersants prepared by controlled radical polymerization having hydrophilic and hydrophobic segments WHITE DANIELA (US) 2003-02-13 US disclosed
US-6462125-B1 RADICALLY POLYMERIZABLE ETHYLENICALLY UNSATURATED MONOMER IN PRESENCE OF A POLYMERIC INITIATOR FORMS THE POLYMERIC BACKBONE SEGMENT OF THE PIGMENT DISPERSANT PPG INDUSTRIES OHIO, INC. 2002-10-08 US disclosed
US-20020123559-A1 PIGMENT DISPRESIONS CONTAINING DISPERSANTS PREPARED BY CONTROLLED RADICAL POLYMERIZATION HAVING HYDROPHILIC AND HYDROPHOBIC SEGMENTS PPG INDUSTRIES OHIO, INC. 2002-09-05 US disclosed
WO-2001044389-A1 PIGMENT DISPERSIONS CONTAINING DISPERSANTS PREPARED BY CONTROLLED RADICAL POLYMERIZATION HAVING HYDROPHILIC AND HYDROPHOBIC SEGMENTS PPG INDUSTRIES OHIO, INC. (US) 2001-06-21 WO disclosed
US-5278054-A Saturating, dissolving in water CHEMIE LINZ GESELLSCHAFT M.B.H. (AT) 1994-01-11 US disclosed
EP-0511526-A1 Process for enzymatic hydrolysis of a carboxylic acid derivate Chemie Linz GmbH (AT) 1992-11-04 EP disclosed
EP-0241559-B1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-10-30 EP disclosed
US-4983751-A Chemical intermediates SAGAMI CHEMICAL RESEARCH CENTER (JP) 1991-01-08 US disclosed
US-4818272-A NONPHYTOTOXICITY FOR CROPS HELICAL STREAMS SAGAMI CHEMICAL RESEARCH CENTER (JP) 1989-04-04 US disclosed
EP-0241559-A1 OXAZOLIDINEDIONE DERIVATIVES, PROCESS FOR THEIR PREPARATION, AND HERBICIDES CONTAINING THE SAME SAGAMI CHEMICAL RESEARCH CENTER (JP) 1987-10-21 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-11958802-B2 Migration-resistant photopolymerization sensitizer F12, F10, PCNA CYP3A4 892/4885TSHR 2947/4885TDP1 3975/4885
US-20220106254-A1 MIGRATION-RESISTANT PHOTOPOLYMERIZATION SENSITIZER F12, F10, PCNA CYP3A4 892/4885TSHR 2947/4885TDP1 3975/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.