Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 3/20 | 0.80 |
| ▸ | PTGER3 | P43115 | 2/20 | 0.68 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.68 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.62 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5219655 | 0.90 | PTGER4 (0.65) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL625968 | 0.89 | PTGER4 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL11885702 | 0.89 | PTGER4 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL4990604 | 0.89 | PTGER4 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL29516796 | 0.89 | PTGER4 (1.00) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL5218204 | 0.89 | PTGER1 (0.65) | PTGER4PTGER3PTGER1 | |
| SCHEMBL4998631 | 0.88 | PTGER4 (0.98) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL4984492 | 0.86 | PTGER4 (0.86) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL4984495 | 0.86 | PTGER4 (0.86) | PTGER4PTGER3PTGER2PTGER1 | |
| SCHEMBL4998635 | 0.86 | PTGER4 (0.86) | PTGER4PTGER3PTGER2PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1339678-B1 | EP4 RECEPTOR SELECTIVE AGONISTS IN THE TREATMENT OF OSTEOPOROSIS | PFIZER PROD INC (US) | 2007-09-26 | — | — | EP | claimed |
| EP-1487437-B1 | USE OF SELECTIVE EP4 RECEPTOR AGONISTS FOR THE TREATMENT OF DISEASES | PFIZER PROD INC (US) | 2006-08-16 | — | — | EP | claimed |