Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 13/20 | 0.56 |
| ▸ | SELP | P16109 | 3/20 | 0.42 |
| ▸ | TYRO3 | Q06418 | 3/20 | 0.42 |
| ▸ | CHEK1 | O14757 | 2/20 | 0.42 |
| ▸ | IKBKB | O14920 | 2/20 | 0.42 |
| ▸ | AURKA | O14965 | 2/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 2/20 | 0.42 |
| ▸ | PAK4 | O96013 | 2/20 | 0.42 |
| ▸ | CHEK2 | O96017 | 2/20 | 0.42 |
| ▸ | ABL1 | P00519 | 2/20 | 0.42 |
| ▸ | EGFR | P00533 | 2/20 | 0.42 |
| ▸ | INSR | P06213 | 2/20 | 0.42 |
| ▸ | LCK | P06239 | 2/20 | 0.42 |
| ▸ | FGFR1 | P11362 | 2/20 | 0.42 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.42 |
| ▸ | CCNA2 | P20248 | 2/20 | 0.42 |
| ▸ | CDK2 | P24941 | 2/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | EPHA2 | P29317 | 2/20 | 0.42 |
| ▸ | CCND3 | P30281 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214293 | 0.90 | CNR2 (0.70) | CNR2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5213113 | 0.86 | CNR2 (0.54) | CNR2MAPTHCRTR1 | |
| SCHEMBL5214601 | 0.86 | CNR2 (0.55) | CNR2MAPTHCRTR1 | |
| SCHEMBL5212581 | 0.84 | CNR2 (0.78) | CNR2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5216176 | 0.83 | CNR2 (0.72) | CNR2MAPK1CYP3A4CYP2D6CYP2C9 | |
| SCHEMBL5213951 | 0.82 | CNR2 (0.65) | CNR2MAP4K4MAPT | |
| SCHEMBL5215861 | 0.82 | CNR2 (0.81) | CNR2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5212098 | 0.82 | CNR2 (0.74) | CNR2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5213027 | 0.81 | CNR2 (0.82) | CNR2CYP3A4CYP2D6CYP2C9CYP2C19 | |
| SCHEMBL5214603 | 0.81 | CNR2 (0.62) | CNR2EGFRCYP2D6CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | claimed |
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | disclosed |
| US-20060240048-A1 | Pyridine derivatives as cb2 receptor modulators | GLAXO GROUP LIMITED (GB) | 2006-10-26 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060240048-A1 | Pyridine derivatives as cb2 receptor modulators | CNR2, CNR1, TRPV1 | CNR2 1/4885SELP 2902/4885TYRO3 2019/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.