Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 9/20 | 0.76 |
| ▸ | PTGER2 | P43116 | 2/20 | 0.68 |
| ▸ | PTGER3 | P43115 | 3/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216126 | 1.00 | PTGER4 (0.76) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5215300 | 0.90 | PTGER4 (0.93) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5215619 | 0.90 | PTGER4 (0.93) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL4933370 | 0.86 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5214074 | 0.84 | PTGER4 (0.68) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5214080 | 0.84 | PTGER4 (0.68) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5732904 | 0.81 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5732901 | 0.81 | PTGER4 (1.00) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5732740 | 0.80 | PTGER4 (0.84) | PTGER4PTGER2PTGER3PTGER1 | |
| SCHEMBL5732737 | 0.80 | PTGER4 (0.84) | PTGER4PTGER2PTGER3PTGER1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | claimed |
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | disclosed |