Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AVPR1A | P37288 | 14/20 | 0.67 |
| ▸ | HTT | P42858 | 3/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 1/20 | 0.46 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | TSHR | P16473 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5214878 | 0.88 | AVPR1A (0.69) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5213181 | 0.82 | AVPR1A (0.77) | AVPR1AHTR7ALDH1A1HPGD | |
| SCHEMBL5212353 | 0.81 | AVPR1A (0.82) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5214851 | 0.81 | AVPR1A (0.81) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5218432 | 0.79 | AVPR1A (1.00) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5215730 | 0.79 | AVPR1A (0.78) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5211608 | 0.79 | AVPR1A (0.84) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5216457 | 0.79 | AVPR1A (0.77) | AVPR1AMAPTALDH1A1KDM4ETSHR | |
| SCHEMBL3105995 | 0.78 | AVPR1A (0.77) | AVPR1AHTTMAPTNPC1RAB9A | |
| SCHEMBL5845867 | 0.77 | AVPR1A (0.76) | AVPR1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1558598-B1 | TRIAZOLE COMPOUNDS FOR THE TREATMENT OF DYSMENORRHOEA | PFIZER LTD (GB) | 2007-07-18 | — | — | EP | claimed |