Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 20/20 | 1.00 |
| ▸ | CYP2D6 | P10635 | 4/20 | 0.62 |
| ▸ | CYP2C19 | P33261 | 4/20 | 0.62 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.62 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.62 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5215162 | 0.93 | CNR2 (0.88) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5216826 | 0.92 | CNR2 (0.85) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5213669 | 0.92 | CNR2 (0.84) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5213103 | 0.92 | CNR2 (0.84) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5214544 | 0.91 | CNR2 (0.83) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5214151 | 0.91 | CNR2 (0.83) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5213433 | 0.91 | CNR2 (0.83) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5212447 | 0.90 | CNR2 (0.82) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5216776 | 0.90 | CNR2 (1.00) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 | |
| SCHEMBL5215897 | 0.90 | CNR2 (0.81) | CNR2CYP2D6CYP2C19CYP2C9CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | claimed |
| EP-1565442-B1 | PYRIDINE DERIVATIVES AS CB2 RECEPTOR MODULATORS | GLAXO GROUP LTD (GB) | 2007-11-14 | — | — | EP | disclosed |