Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGER4 | P35408 | 16/20 | 0.59 |
| ▸ | PTGER2 | P43116 | 8/20 | 0.59 |
| ▸ | PTGER3 | P43115 | 7/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5216558 | 0.86 | PTGER4 (0.79) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5216532 | 0.86 | PTGER4 (0.79) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5216562 | 0.86 | PTGER4 (0.79) | PTGER4PTGER2PTGER3 | |
| SCHEMBL7245447 | 0.86 | PTGER4 (0.72) | PTGER4PTGER2PTGER3 | |
| SCHEMBL7245443 | 0.86 | PTGER4 (0.72) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5216476 | 0.83 | PTGER4 (0.57) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214661 | 0.82 | PTGER4 (0.58) | PTGER4PTGER2PTGER3 | |
| SCHEMBL5214669 | 0.82 | PTGER4 (0.58) | PTGER4PTGER2PTGER3 | |
| SCHEMBL14030713 | 0.81 | PTGER4 (0.66) | PTGER4PTGER2PTGER3 | |
| SCHEMBL14464329 | 0.80 | PTGER4 (0.56) | PTGER4PTGER2PTGER3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1408961-B1 | 2 PYRROLIDONE DERIVATIVES AS PROSTANOID AGONISTS | HOFFMANN LA ROCHE (CH) | 2007-07-11 | — | — | EP | disclosed |