SCHEMBL521654

SCHEMBL521654

COC(=O)CC[Si](Cl)(Cl)Cl

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 4/20 0.57
LMNA P02545 3/20 0.46
KDM4E B2RXH2 1/20 0.46
KMT2A Q03164 2/20 0.43
MEN1 O00255 1/20 0.43
CA12 O43570 2/20 0.41
CA14 Q9ULX7 2/20 0.41
RECQL P46063 1/20 0.41
ALDH1A1 P00352 3/20 0.40
HSD17B10 Q99714 2/20 0.40
MGAM O43451 1/20 0.40
GAA P10253 1/20 0.40
SI P14410 1/20 0.40
MGAM2 Q2M2H8 1/20 0.40
MAPT P10636 1/20 0.40
HTT P42858 1/20 0.40
TET2 Q6N021 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.36
EPHX2 P34913 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10411810 0.86 TSHR (0.61) TSHRLMNAKDM4EKMT2AMEN1
SCHEMBL10362918 0.84 TSHR (0.58) TSHRLMNAKMT2AMEN1CA12
SCHEMBL8593759 0.83 TSHR (0.47) TSHRLMNAKDM4EKMT2ARECQL
SCHEMBL524099 0.83 TSHR (0.55) TSHRLMNAKDM4EKMT2AMEN1
SCHEMBL10364716 0.83 TSHR (0.55) TSHRLMNAKDM4EKMT2AMEN1
SCHEMBL19770561 0.82 TSHR (0.56) TSHRLMNAKMT2ARECQLALDH1A1
SCHEMBL19770532 0.82 TSHR (0.56) TSHRLMNAKMT2ARECQLALDH1A1
SCHEMBL19770574 0.82 TSHR (0.56) TSHRLMNAKMT2ARECQLALDH1A1
SCHEMBL9244364 0.82 TSHR (0.56) TSHRLMNAKMT2ARECQLALDH1A1
SCHEMBL755820 0.82 TSHR (0.56) TSHRLMNAKMT2ARECQLALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 366 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116496500-A Combined hard mask and ARC in single layer compositions for KrF microlithography 上海艾深斯科技有限公司 2023-07-28 CN claimed
EP-2714225-B1 METHOD OF SEPARATION OF LIPID AND BIOLOGICAL MOLECULAR SPECIES USING HIGH PURITY CHROMATOGRAPHIC MATERIALS WATERS TECHNOLOGIES CORP (US) 2020-11-11 EP claimed
US-20200332028-A1 CHARGED SURFACE REVERSED PHASE CHROMATOGRAPHIC MATERIALS METHOD FOR ANALYSIS OF GLYCANS MODIFIED WITH AMPHIPATHIC, STRONGLY BASIC MOIETIES WATERS TECHNOLOGIES CORPORATION 2020-10-22 US claimed
CN-111718711-A Composite material and preparation method thereof TCL集团股份有限公司 2020-09-29 CN claimed
EP-3687652-A1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES Waters Technologies Corporation (US) 2020-08-05 EP claimed
CN-111405934-A High purity chromatographic materials comprising ionizable modifiers for retention of acidic analytes 沃特世科技公司 2020-07-10 CN claimed
US-20190126241-A1 HIGH PURITY CHROMATOGRAPHIC MATERIALS COMPRISING AN IONIZABLE MODIFIER FOR RETENTION OF ACIDIC ANALYTES WATERS TECHNOLOGIES CORPORATION 2019-05-02 US claimed
WO-2018011675-A1 GRAPHENE COMPOUND, METHOD FOR FORMING GRAPHENE COMPOUND, AND POWER STORAGE DEVICE SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-01-18 WO claimed
US-20180019462-A1 Graphene Compound, Method for Forming Graphene Compound, and Power Storage Device SEMICONDUCTOR ENERGY LABORATORY CO., LTD. (JP) 2018-01-18 US claimed
CN-104311593-A Synthesis method of mono functional group octa-polysilsesquioxane UNIV SHANGHAI 2015-01-28 CN claimed
US-20030042140-A1 Chemical furface for control of electroosmosis by an applied external voltage field ARIZONA BOARD OF REGENTS 2003-03-06 US claimed
US-6488831-B1 Chemical surface for control of electroosmosis by an applied external voltage field ARIZONA BOARD OF REGENTS ARIZONA STATE UNIVERSITY 2002-12-03 US claimed
EP-1060389-A1 CHEMICAL SURFACE FOR CONTROL OF ELECTROOSMOSIS BY AN APPLIED EXTERNAL VOLTAGE FIELD Arizona Board of Regents (US) 2000-12-20 EP claimed
WO-1999045377-A1 CHEMICAL SURFACE FOR CONTROL OF ELECTROOSMOSIS BY AN APPLIED EXTERNAL VOLTAGE FIELD ARIZONA BOARD OF REGENTS (US) 1999-09-10 WO claimed
EP-0637902-B1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC (US) 1999-03-31 EP claimed
EP-0637902-A1 Metallic foil with adhesion promoting layer GOULD ELECTRONICS INC. (US) 1995-02-08 EP claimed
EP-0201286-B1 BONDED PHASE OF SILICA AND CARBOALKOXYALKYL SILANES FOR SOLID PHASE EXTRACTION J.T. BAKER INC. (US) 1990-10-03 EP claimed
US-4680120-A Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction J. T. BAKER CHEMICAL COMPANY (US) 1987-07-14 US claimed
US-4640909-A Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction J. T. BAKER CHEMICAL COMPANY (US) 1987-02-03 US claimed
EP-0201286-A2 Bonded phase of silica and carboalkoxyalkyl silanes for solid phase extraction J.T. BAKER INC. (US) 1986-11-12 EP claimed