Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA2A | P29274 | 19/20 | 0.51 |
| ▸ | ADORA3 | P0DMS8 | 13/20 | 0.49 |
| ▸ | ADORA2B | P29275 | 13/20 | 0.49 |
| ▸ | ADORA1 | P30542 | 13/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4222762 | 1.00 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4222765 | 1.00 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL4222757 | 1.00 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| Trifluoroacetic Acid SCHEMBL4220188 | 0.93 | ADORA2A (0.45) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2831775 | 0.92 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2831776 | 0.92 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL2831778 | 0.92 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL9988022 | 0.92 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| SCHEMBL12049780 | 0.92 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 | |
| Trifluoroacetic Acid SCHEMBL4379636 | 0.89 | ADORA2A (0.51) | ADORA2AADORA3ADORA2BADORA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1861412-A1 | ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY | Novartis AG (CH) | 2007-12-05 | — | — | EP | disclosed |
| WO-2006097260-A1 | ADENOSINE DERIVATIVES HAVING A2A RECEPTOR ACTIVITY | NOVARTIS AG (CH) | 2006-09-21 | — | — | WO | disclosed |