Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK1D | P48730 | 1/20 | 0.49 |
| ▸ | GSK3B | P49841 | 8/20 | 0.48 |
| ▸ | CDK4 | P11802 | 2/20 | 0.45 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.45 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.45 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.45 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.45 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.42 |
| ▸ | MAPK9 | P45984 | 2/20 | 0.42 |
| ▸ | PRKD3 | O94806 | 1/20 | 0.42 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.42 |
| ▸ | CSNK1A1 | P48729 | 1/20 | 0.42 |
| ▸ | CLK2 | P49760 | 1/20 | 0.42 |
| ▸ | GSK3A | P49840 | 1/20 | 0.42 |
| ▸ | CSNK1G2 | P78368 | 1/20 | 0.42 |
| ▸ | TAOK1 | Q7L7X3 | 1/20 | 0.42 |
| ▸ | MINK1 | Q8N4C8 | 1/20 | 0.42 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.42 |
| ▸ | PRKD2 | Q9BZL6 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5890227 | 0.89 | CSNK1D (0.49) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5215526 | 0.89 | CSNK1D (0.47) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5216017 | 0.87 | CSNK1D (0.46) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5217719 | 0.86 | CSNK1D (0.46) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5215590 | 0.86 | CSNK1D (0.46) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5216364 | 0.85 | CSNK1D (0.44) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5890439 | 0.84 | CSNK1D (0.47) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5214451 | 0.84 | CSNK1D (0.51) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5890649 | 0.83 | CSNK1D (0.51) | CSNK1DGSK3BCDK4MAPK13MAPK12 | |
| SCHEMBL5891079 | 0.83 | CSNK1D (0.50) | CSNK1DGSK3BCDK4MAPK13MAPK12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1423389-B1 | PYRAZOLO-PYRIDINES FOR THE TREATMENT OF HERPES INFECTIONS | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | EP | claimed |
| EP-1423389-B1 | PYRAZOLO-PYRIDINES FOR THE TREATMENT OF HERPES INFECTIONS | SMITHKLINE BEECHAM CORP (US) | 2007-06-06 | — | — | EP | disclosed |