⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5122282 | 0.73 | — | — | |
| SCHEMBL9140690 | 0.70 | — | — | |
| SCHEMBL5747213 | 0.67 | — | — | |
| SCHEMBL9338485 | 0.65 | — | — | |
| SCHEMBL349235 | 0.63 | — | — | |
| SCHEMBL8936509 | 0.60 | — | — | |
| SCHEMBL29556006 | 0.60 | — | — | |
| SCHEMBL4730422 | 0.60 | — | — | |
| SCHEMBL873801 | 0.60 | — | — | |
| SCHEMBL104463 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2000501738-A | — | — | 2000-02-15 | — | — | JP | claimed |
| US-5912366-A | CHEMICAL INTERMEDIATES FOR GEMCITABINE AN ANTITUMOR AGENT | ELI LILLY AND COMPANY (US) | 1999-06-15 | — | — | US | claimed |
| US-5756775-A | Process to make α,α-difluoro-β-hydroxyl thiol esters | ELI LILLY AND COMPANY (US) | 1998-05-26 | — | — | US | claimed |
| WO-1997021719-A1 | α, α-DIFLUORO-β-HYDROXY THIOL ESTERS AND THEIR SYNTHESIS | ELI LILLY AND COMPANY (US) | 1997-06-19 | — | — | WO | claimed |
| EP-0779275-A2 | Alpha, Alpha - Difluoro-beta -hydroxy thiol esters and their synthesis | ELI LILLY AND COMPANY (US) | 1997-06-18 | — | — | EP | claimed |
| EP-1467992-B1 | ANTIMICROBIAL DIHYDROTHIAZINE AND DIHYDROTHIOPYRAN OXAZOLIDINONES | PHARMACIA & UPJOHN CO LLC (US) | 2007-08-08 | — | — | EP | disclosed |
| US-7141570-B2 | N-aryl-2-oxazolidinone-5-carboxamides and their derivatives | PHARMACIA & UPJOHN COMPANY (US) | 2006-11-28 | — | — | US | disclosed |
| EP-1565186-B1 | N-(4-(PIPERAZIN-1-YL)-PHENYL-2-OXAZOLIDINONE-5-CARBOXAMIDE DERIVATES AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | PHARMACIA & UPJOHN CO LLC (US) | 2006-11-02 | — | — | EP | disclosed |
| US-7101874-B2 | Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones | PHARMACIA AND UPJOHN COMPANY (US) | 2006-09-05 | — | — | US | disclosed |
| EP-1660488-A1 | NOVEL ANTIMICROBIAL ARYLOXAZOLIDINONE COMPOUNDS | Warner-Lambert Company LLC (US) | 2006-05-31 | — | — | EP | disclosed |
| EP-1565186-A1 | N-(4-(PIPERAZIN-1-YL)-PHENYL-2-OXAZOLIDINONE-5-CARBOXAMIDE DERIVATES AND RELATED COMPOUNDS AS ANTIBACTERIAL AGENTS | Pharmacia & Upjohn Company LLC (US) | 2005-08-24 | — | — | EP | disclosed |
| US-20050143376-A1 | Antimicrobial dihydrothiazine and dihydrothiopyran oxazolidinones | GORDEEV MIKHAIL F (US) | 2005-06-30 | — | — | US | disclosed |
| US-5756775-A | Process to make α,α-difluoro-β-hydroxyl thiol esters | ELI LILLY AND COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| US-5756775-A | Process to make α,α-difluoro-β-hydroxyl thiol esters | ELI LILLY AND COMPANY (US) | 1998-05-26 | — | — | US | disclosed |
| WO-1997021719-A1 | α, α-DIFLUORO-β-HYDROXY THIOL ESTERS AND THEIR SYNTHESIS | ELI LILLY AND COMPANY (US) | 1997-06-19 | — | — | WO | disclosed |
| WO-1997021719-A1 | α, α-DIFLUORO-β-HYDROXY THIOL ESTERS AND THEIR SYNTHESIS | ELI LILLY AND COMPANY (US) | 1997-06-19 | — | — | WO | disclosed |
| EP-0779275-A2 | Alpha, Alpha - Difluoro-beta -hydroxy thiol esters and their synthesis | ELI LILLY AND COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0779275-A2 | Alpha, Alpha - Difluoro-beta -hydroxy thiol esters and their synthesis | ELI LILLY AND COMPANY (US) | 1997-06-18 | — | — | EP | disclosed |
| EP-0677527-A1 | Process for preparing 2,2-difluoroketene silyl O,S-acetals and alpha, alpha-difluoro-beta-silyloxy-1,3-dioxolane-4-propanoic acid O,S-esters | ELI LILLY AND COMPANY (US) | 1995-10-18 | — | — | EP | disclosed |
| US-5428176-A | Contacting a difluorothioacetate with a halosilane in presence of reducing agent | ELI LILLY AND COMPANY (US) | 1995-06-27 | — | — | US | disclosed |