SCHEMBL5217342

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5215902	0.94	ESR1 (0.54)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5214926	0.93	ESR1 (0.55)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5215998	0.90	KMT2A (0.51)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5215949	0.88	KMT2A (0.52)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5213728	0.87	ESR1 (0.60)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5216990	0.86	KMT2A (0.52)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5221501	0.86	KMT2A (0.49)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5214655	0.86	SRC (0.50)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5219260	0.83	CA1 (0.64)	ESR1KMT2AMAPTMAPK1NPSR1
	SCHEMBL5215071	0.83	ESR1 (0.47)	ESR1KMT2AMAPTMAPK1NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.