Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A1 | P18405 | 4/20 | 0.64 |
| ▸ | SRD5A2 | P31213 | 4/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | SHBG | P04278 | 1/20 | 0.47 |
| ▸ | SERPINA6 | P08185 | 1/20 | 0.47 |
| ▸ | G6PD | P11413 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11416876 | 1.00 | SRD5A1 (0.64) | SRD5A1SRD5A2CYP2C19LMNASHBG | |
| SCHEMBL9022075 | 1.00 | SRD5A1 (0.64) | SRD5A1SRD5A2CYP2C19LMNASHBG | |
| SCHEMBL9022079 | 1.00 | SRD5A1 (0.64) | SRD5A1SRD5A2CYP2C19LMNASHBG | |
| SCHEMBL29059721 | 0.91 | SRD5A1 (0.64) | SRD5A1CYP2C19LMNASHBGSERPINA6 | |
| SCHEMBL14184971 | 0.89 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL4012146 | 0.89 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL14214561 | 0.89 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL4012144 | 0.89 | SRD5A1 (0.61) | SRD5A1SRD5A2 | |
| SCHEMBL14359403 | 0.88 | SRD5A1 (0.50) | SRD5A1SRD5A2CYP2C19LMNASHBG | |
| SCHEMBL5215184 | 0.87 | SRD5A1 (0.49) | SRD5A1SRD5A2CYP2C19LMNASHBG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1420796-A4 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO INC (US) | 2007-07-11 | — | — | EP | disclosed |
| EP-1420796-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | Merck & Co., Inc. (US) | 2004-05-26 | — | — | EP | disclosed |
| WO-2003011302-A1 | ANDROGEN RECEPTOR MODULATORS AND METHODS OF USE THEREOF | MERCK & CO., INC. (US) | 2003-02-13 | — | — | WO | disclosed |