SCHEMBL5218703

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL5216392	0.85	ESR1 (0.45)	ESR1MTORCD74MIFESR2
	SCHEMBL5220996	0.81	ESR1 (0.50)	ESR1MTORKDM4ETP53CYP1A2
	SCHEMBL5215468	0.78	ESR1 (0.44)	ESR1MGLLABHD6KDM4ETP53
	SCHEMBL5214604	0.74	ESR1 (0.48)	ESR1KDM4ETP53CYP1A2CYP3A4
	SCHEMBL5221734	0.72	MTOR (0.46)	ESR1GCGRMTORCD74MIF
	SCHEMBL5216958	0.72	ESR1 (0.54)	ESR1KDM4ETP53CYP1A2CYP3A4
	SCHEMBL5221388	0.71	ESR1 (0.45)	ESR1CD74MIFKDM4EALDH1A1
	SCHEMBL5217890	0.70	ESR1 (0.48)	ESR1ESR2KDM4ETP53CYP1A2
	SCHEMBL29234887	0.67	CXCR2 (0.47)	KDM4ETP53CYP1A2CYP3A4MAPT
	SCHEMBL6834900	0.67	ESR1 (0.48)	ESR1KDM4ETP53CYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.