Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.91 |
| ▸ | DPP8 | Q6V1X1 | 9/20 | 0.75 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.75 |
| ▸ | DPP9 | Q86TI2 | 6/20 | 0.75 |
| ▸ | PREP | P48147 | 6/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL5216234 | 0.95 | DPP4 (0.83) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL4635508 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL4635510 | 0.85 | DPP4 (1.00) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL12921251 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL6605407 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL5215649 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP7DPP9PREP | |
| Hydrochloric Acid SCHEMBL5218591 | 0.82 | DPP4 (0.98) | DPP4DPP8DPP7DPP9PREP | |
| Hydrochloric Acid SCHEMBL6701714 | 0.80 | DPP4 (0.74) | DPP4DPP8DPP7DPP9 | |
| SCHEMBL8295116 | 0.79 | DPP4 (0.71) | DPP4DPP8DPP7DPP9PREP | |
| SCHEMBL3830920 | 0.79 | DPP4 (0.75) | DPP4DPP8DPP7DPP9PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-B1 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-08-22 | — | — | EP | claimed |
| US-7183290-B2 | Fluoropyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-27 | — | — | US | disclosed |
| US-7183290-B2 | Fluoropyrrolidines as dipeptidyl peptidase inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2007-02-27 | — | — | US | disclosed |