Propyne

Propyne

SCHEMBL521923

C#CC

nearest known ligand 0.00

Full drug profile on Sugi Atlas →

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Propyne SCHEMBL2031 1.00
Propyne SCHEMBL1330783 1.00
Propyne SCHEMBL9522893 1.00
Propyne SCHEMBL830325 0.93
Propyne SCHEMBL10631146 0.93
Propyne SCHEMBL22983240 0.93
Propyne SCHEMBL6886770 0.93
Propyne SCHEMBL22749791 0.93
Propyne SCHEMBL7158451 0.93
Propyne SCHEMBL20557227 0.93

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 330 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108477173-B Heterocyclic compounds as pesticides 拜耳农作物科学股份公司 2021-07-02 CN claimed
US-10689348-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2020-06-23 US claimed
US-10435374-B2 Heterocyclic compounds as pesticides BAYER CROPSCIENCE AG (DE) 2019-10-08 US claimed
US-20140243375-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2014-08-28 US claimed
EP-2763970-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS Syngenta Participations AG (CH) 2014-08-13 EP claimed
WO-2013050302-A1 ISOXAZOLINE DERIVATIVES AS INSECTICIDAL COMPOUNDS SYNGENTA PARTICIPATIONS AG (CH) 2013-04-11 WO claimed
JP-2007506716-A 2007-03-22 JP claimed
US-20070043010-A1 Quinazoline derivatives ASTRAZENECA UK LIMITED (GB) 2007-02-22 US claimed
EP-1670786-A1 QUINAZOLINE DERIVATIVES Astrazeneca AB (SE) 2006-06-21 EP claimed
WO-2005030757-A1 QUINAZOLINE DERIVATIVES ASTRAZENECA AB (SE) 2005-04-07 WO claimed
EP-0688555-A2 Hair-growing agent TANABE SEIYAKU CO., LTD. (JP) 1995-12-27 EP claimed
CN-112996800-B Novel proteolytically targeted chimeras (PROTAC) and derivatives thereof as SMARCA2 and/or SMARCA4 degrading agents 勃林格殷格翰国际有限公司 2024-06-25 CN disclosed
CN-118159420-A Cover film 富士胶片株式会社 2024-06-07 CN disclosed
CN-118043201-A Cover film 富士胶片株式会社 2024-05-14 CN disclosed
EP-4357020-A2 ASYMMETRIC PHASE TRANSFER CATALYSIS Merck Sharp & Dohme LLC (US) 2024-04-24 EP disclosed
EP-0419215-A2 Process for preparing 4-substituted azetidinones ELI LILLY AND COMPANY (US) 1991-03-27 EP disclosed
US-4994453-A Treating asthma, diabetes, obesity, immunosuppression FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1991-02-19 US disclosed
US-4925849-A DIURETICS, HYPOTENSIVE AGENTS, CARIOTONIC AGENTS AND ANTIEDEMIC AGENTS FUJISAWA PHARMACEUTICAL COMPANY, LTD. (JP) 1990-05-15 US disclosed
CN-1031376-A Pyrazolopyridine compound and preparation method thereof FUJISAWA PHARMACEUTICAL CO (JP) 1989-03-01 CN disclosed
EP-0299209-A2 Pyrazolopyridine compound and processes for preparation thereof FUJISAWA PHARMACEUTICAL CO., LTD. (JP) 1989-01-18 EP disclosed