Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2652923 | 0.86 | GCK (0.59) | KCNH2GCK | |
| SCHEMBL12742382 | 0.86 | GCK (0.64) | KCNH2GCK | |
| SCHEMBL9892933 | 0.84 | GCK (0.62) | KCNH2GCK | |
| SCHEMBL1133220 | 0.83 | GCK (0.59) | KCNH2GCK | |
| SCHEMBL1137113 | 0.83 | KCNH2 (0.55) | KCNH2GCK | |
| SCHEMBL2645769 | 0.82 | GCK (0.60) | KCNH2GCK | |
| SCHEMBL2645766 | 0.82 | GCK (0.60) | KCNH2GCK | |
| SCHEMBL2668947 | 0.82 | GCK (0.60) | KCNH2GCK | |
| SCHEMBL2664457 | 0.81 | GCK (0.57) | KCNH2GCK | |
| SCHEMBL2646843 | 0.81 | GCK (0.63) | KCNH2GCK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1572670-B1 | 5-SUBSTITUTED-PYRAZINE OR -PYRIDINE GLUCOKINASE ACTIVATORS | HOFFMANN LA ROCHE (CH) | 2007-08-22 | — | — | EP | claimed |