Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 9/20 | 0.36 |
| ▸ | NPC1 | O15118 | 8/20 | 0.36 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.36 |
| ▸ | DGAT1 | O75907 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.35 |
| ▸ | TARBP2 | Q15633 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 1/20 | 0.35 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4473392 | 0.85 | NPC1 (0.39) | RAB9ANPC1RXFP1DGAT1MAPT | |
| SCHEMBL4469328 | 0.74 | TARBP2 (0.39) | RAB9ANPC1RXFP1DGAT1MAPT | |
| SCHEMBL4473360 | 0.73 | TARBP2 (0.41) | RAB9ANPC1RXFP1DGAT1MAPT | |
| SCHEMBL6221124 | 0.71 | TARBP2 (0.39) | RAB9ANPC1RXFP1DGAT1MAPT | |
| SCHEMBL4482083 | 0.71 | TARBP2 (0.39) | RAB9ANPC1RXFP1DGAT1MAPT | |
| SCHEMBL4478483 | 0.69 | NPC1 (0.43) | RAB9ANPC1RXFP1MAPTKMT2A | |
| SCHEMBL4475581 | 0.67 | IKBKB (0.43) | RAB9ANPC1MAPTKMT2AKDM4E | |
| SCHEMBL4462656 | 0.66 | TARBP2 (0.62) | RAB9ANPC1MAPTKMT2AKDM4E | |
| SCHEMBL5217558 | 0.66 | TARBP2 (0.49) | RAB9ANPC1RXFP1DGAT1MAPT | |
| SCHEMBL15166547 | 0.66 | KMT2A (0.38) | RAB9ANPC1RXFP1DGAT1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1480640-B1 | PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR MODULATORS | LILLY CO ELI (US) | 2007-08-15 | — | — | EP | disclosed |