Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5227120 | 0.90 | — | — | |
| SCHEMBL5224603 | 0.86 | — | — | |
| SCHEMBL5228642 | 0.82 | CYP1A2 (0.47) | CYP3A4 | |
| SCHEMBL4036368 | 0.82 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL5359417 | 0.80 | CYP3A4 (0.53) | CYP3A4 | |
| SCHEMBL4858090 | 0.80 | CYP3A4 (0.65) | CYP3A4 | |
| SCHEMBL6257407 | 0.78 | — | — | |
| SCHEMBL5901622 | 0.78 | — | — | |
| SCHEMBL6028488 | 0.78 | CYP3A4 (0.59) | CYP3A4 | |
| SCHEMBL4334506 | 0.78 | CYP3A4 (0.59) | CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1806346-A1 | Substituted piperazine compounds and their use as fatty acid oxidation inhibitors | CV THERAPEUTICS, INC. (US) | 2007-07-11 | — | — | EP | disclosed |