Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 9/20 | 0.49 |
| ▸ | KMO | O15229 | 1/20 | 0.49 |
| ▸ | FFAR4 | Q5NUL3 | 7/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 7/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.46 |
| ▸ | CACNA1C | Q13936 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5032985 | 0.85 | HRH3 (0.58) | HRH3 | |
| SCHEMBL5672639 | 0.84 | HRH3 (0.48) | HRH3 | |
| SCHEMBL5032790 | 0.82 | HRH3 (0.55) | HRH3 | |
| SCHEMBL5034855 | 0.82 | HRH3 (0.55) | HRH3 | |
| SCHEMBL5030411 | 0.80 | HRH3 (0.54) | HRH3 | |
| SCHEMBL7393118 | 0.80 | HRH3 (0.45) | HRH3FFAR1 | |
| SCHEMBL16808245 | 0.79 | HRH3 (0.51) | HRH3 | |
| SCHEMBL7799417 | 0.79 | FFAR4 (0.52) | FFAR4FFAR1CYP2C9CACNA1C | |
| SCHEMBL176970 | 0.79 | HRH3 (0.49) | HRH3 | |
| SCHEMBL2093469 | 0.79 | HRH3 (0.49) | HRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1315710-B1 | AMINOALKOXYBENZOYL-BENZOFURAN OR BENZOTHIOPHENE DERIVATIVES, METHOD FOR PREPARING SAME AND COMPOSITIONS CONTAINING SAME | SANOFI AVENTIS (FR) | 2007-04-25 | — | — | EP | disclosed |