Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 1/20 | 0.70 |
| ▸ | DEGS1 | O15121 | 1/20 | 0.56 |
| ▸ | RAB9A | P51151 | 2/20 | 0.54 |
| ▸ | NPC1 | O15118 | 1/20 | 0.54 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 5/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.52 |
| ▸ | SLC16A3 | O15427 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | FDPS | P14324 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1954449 | 0.83 | GFER (0.80) | GFERDEGS1RAB9ARXFP1MEN1 | |
| SCHEMBL1955845 | 0.82 | GFER (0.78) | GFERDEGS1RAB9ANPC1MEN1 | |
| SCHEMBL1310079 | 0.82 | GFER (0.78) | GFERDEGS1RAB9ARXFP1MEN1 | |
| SCHEMBL9281809 | 0.81 | GFER (0.76) | GFERDEGS1RAB9ANPC1RXFP1 | |
| SCHEMBL14413339 | 0.81 | GFER (0.76) | GFERDEGS1RAB9ARXFP1MEN1 | |
| SCHEMBL1307732 | 0.81 | GFER (0.76) | GFERDEGS1RAB9AMEN1KMT2A | |
| SCHEMBL1308410 | 0.81 | GFER (0.76) | GFERRAB9AMEN1KMT2AKDM4E | |
| SCHEMBL11803827 | 0.79 | KDM4E (0.67) | MEN1KMT2AKDM4EALDH1A1NR1H4 | |
| SCHEMBL3655566 | 0.79 | DEGS1 (0.65) | GFERDEGS1RAB9ANPC1MEN1 | |
| SCHEMBL5220662 | 0.79 | CNR1 (0.74) | GFERDEGS1NPC1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756044-A1 | THERAPEUTIC COMPOUNDS | AstraZeneca AB (SE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005115972-A1 | THERAPEUTIC COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | WO | disclosed |