Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 20/20 | 0.73 |
| ▸ | PREP | P48147 | 2/20 | 0.49 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.49 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.49 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14587268 | 0.86 | DPP4 (0.66) | DPP4PREPDPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL5219259 | 0.85 | DPP4 (0.65) | DPP4PREPDPP8DPP7DPP9 | |
| Hydrochloric Acid SCHEMBL5205598 | 0.84 | DPP4 (0.97) | DPP4 | |
| SCHEMBL8267018 | 0.83 | DPP4 (1.00) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5204236 | 0.82 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5206737 | 0.82 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL5206597 | 0.81 | DPP4 (0.97) | DPP4DPP8DPP9 | |
| Hydrochloric Acid SCHEMBL6172699 | 0.80 | DPP4 (0.95) | DPP4DPP8DPP9 | |
| SCHEMBL15238166 | 0.79 | DPP4 (0.81) | DPP4 | |
| SCHEMBL1346883 | 0.77 | DPP4 (0.59) | DPP4PREPDPP8DPP7DPP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1399433-B1 | FLUOROPYRROLIDINES AS DIPEPTIDYL PEPTIDASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-08-22 | — | — | EP | claimed |