Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226051 | 0.92 | KDR (0.52) | KDRAURKA | |
| SCHEMBL5227736 | 0.92 | KDR (0.55) | KDRAURKA | |
| SCHEMBL4978362 | 0.91 | KDR (0.68) | KDRAURKA | |
| SCHEMBL4976774 | 0.90 | KDR (0.54) | KDRAURKA | |
| SCHEMBL5225921 | 0.90 | KDR (0.55) | KDRAURKA | |
| SCHEMBL5225503 | 0.90 | KDR (0.58) | KDRAURKA | |
| SCHEMBL5222967 | 0.89 | KDR (0.54) | KDRAURKA | |
| SCHEMBL5225341 | 0.89 | KDR (0.59) | KDRAURKA | |
| SCHEMBL4983361 | 0.88 | KDR (0.53) | KDRAURKA | |
| SCHEMBL5223748 | 0.88 | KDR (0.52) | KDRAURKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| US-7338959-B2 | Diamino-pyrimidines and their use as angiogenesis inhibitors | SMITHKLINE BEECHAM CORPORATION (US) | 2008-03-04 | — | — | US | disclosed |
| EP-1487824-B1 | DIAMINO-PYRIMIDINES AND THEIR USE AS ANGIOGENESIS INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2007-06-20 | — | — | EP | disclosed |