SCHEMBL522316

SCHEMBL522316

ClC(Cl)(Cl)c1ccccc1

nearest known ligand 1.00 ✓ in ChEMBL — recovers established targets

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 1.00
CYP1A2 P05177 1/20 0.50
KCNN4 O15554 5/20 0.47
ALDH1A1 P00352 3/20 0.47
LMNA P02545 1/20 0.41
MAPK1 P28482 1/20 0.41
TAAR1 Q96RJ0 1/20 0.38
ALOX15 P16050 1/20 0.38
PTPN1 P18031 1/20 0.36
ESR1 P03372 1/20 0.36
CYP3A4 P08684 1/20 0.36
ESR2 Q92731 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL28581636 0.97 TSHR (0.93) TSHRCYP1A2KCNN4ALDH1A1LMNA
SCHEMBL30740351 0.97 TSHR (0.93) TSHRCYP1A2KCNN4ALDH1A1LMNA
Hydrochloric Acid SCHEMBL28846684 0.94 TSHR (0.88) TSHRCYP1A2KCNN4ALDH1A1LMNA
Ethane SCHEMBL28666542 0.94 TSHR (0.88) TSHRCYP1A2KCNN4ALDH1A1LMNA
Methylene Chloride SCHEMBL28935108 0.91 TSHR (0.82) TSHRCYP1A2KCNN4ALDH1A1LMNA
Biphenyl SCHEMBL28542053 0.91 TSHR (0.82) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Methyl Alcohol SCHEMBL28788630 0.91 TSHR (0.82) TSHRCYP1A2KCNN4ALDH1A1MAPK1
Hydrochloric Acid SCHEMBL19409802 0.88 TSHR (0.78) TSHRCYP1A2KCNN4ALDH1A1LMNA
P-Xylene SCHEMBL29242628 0.86 TSHR (0.74) TSHRCYP1A2KCNN4ALDH1A1LMNA
O-Xylene SCHEMBL29242624 0.86 TSHR (0.74) TSHRCYP1A2KCNN4ALDH1A1LMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 4733 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-122080553-A High-temperature-resistant sealing rubber material and preparation method thereof 2026-05-26 CN claimed
EP-4743438-A1 AN IMPROVED PROCESS FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2026-05-20 EP claimed
CN-122042872-A Separation determination of ibutinib SM based on gas chromatography3And method for impurity thereof 重庆华邦制药有限公司 2026-05-15 CN claimed
EP-4717667-A1 FLUOROSULFONYLIMIDE SALT AND PREPARATION METHOD THEREFOR EP CHEMTECH CO., LTD. (KR) 2026-04-01 EP claimed
EP-4665705-A1 A PROCESSES FOR THE PREPARATION OF BENZONITRILE COMPOUNDS FROM THE CORRESPONDING BENZOTRICHLORIDE COMPOUNDS Aarti Industries Limited (IN) 2025-12-24 EP claimed
US-12404231-B2 Method for preparing trifluoromethyl aromatic compound JINGDEZHEN FUSHINE LIFE TECHNOLOGY CO., LTD. (CN) 2025-09-02 US claimed
US-20250257028-A1 Method for Preparing Trifluoromethyl Aromatic Compound JINGDEZHEN FUSHINE LIFE TECHNOLOGY CO., LTD. (CN) 2025-08-14 US claimed
US-20250198641-A1 INDOOR AIR CLEANING SYSTEM MICROJET TECHNOLOGY CO., LTD. (TW) 2025-06-19 US claimed
EP-4571207-A1 INDOOR AIR CLEANING SYSTEM Microjet Technology Co., Ltd. (TW) 2025-06-18 EP claimed
CN-120160227-A Indoor air cleaning system 研能科技股份有限公司 2025-06-17 CN claimed
US-4080378-A REACTING A CARBOXYLIC ACID ESTER WITH A TRICHLOROMETHYL SUBSTITUTED AROMATIC COMPOUND IN THE PRESENCE OF A MOLYBDENUM CATALYST DYNAMIT NOBEL AKTIENGESELLSCHAFT (DT) 1978-03-21 US claimed
US-4062713-A Photodosimeter film badge BECKMAN INSTRUMENTS, INC. (US) 1977-12-13 US claimed
US-4061688-A FLUOSULFONIC ACID CATALYST, HYDROGEN FLUORIDE HOOKER CHEMICALS & PLASTICS CORPORATION (US) 1977-12-06 US claimed
US-4059610-A Process for preparing isocyanic acid derivatives KAO SOAP CO., LTD. (JA) 1977-11-22 US claimed
US-4048033-A FROM THE PARTIALLY CHLORINATED METHYLBENZENE AND CHLORINE, ULTRAVIOLET RADIATION MITSUBISHI GAS CHEMICAL COMPANY, INC. (JA) 1977-09-13 US claimed
US-4021600-A Slurry polymerization process E. I. DU PONT DE NEMOURS AND COMPANY (US) 1977-05-03 US claimed
US-4013817-A HALOGENATED AROMATIC HYDROCARBON BRIDGESTONE TIRE COMPANY LIMITED (JA) 1977-03-22 US claimed
US-3992275-A Low gloss ultraviolet curable coatings utilizing α,α,α-trichlorotoluene as a photoinitiator CELANESE CORPORATION (US) 1976-11-16 US claimed
US-3950445-A Process for the production of benzotrifluoride LONZA LTD. (CH) 1976-04-13 US claimed
US-3948966-A METAL CHLORIDE-DIMETHYLFORMAMIDE CATALYSTS KAO SOAP CO., LTD. (JA) 1976-04-06 US claimed