Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | CTH | P32929 | 1/20 | 0.33 |
| ▸ | CBS | P35520 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | THRB | P10828 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17786013 | 0.84 | — | — | |
| SCHEMBL3057906 | 0.79 | — | — | |
| SCHEMBL30288115 | 0.76 | — | — | |
| SCHEMBL11025266 | 0.76 | TDP1 (0.30) | — | |
| SCHEMBL7047073 | 0.73 | TSHR (0.30) | TSHRCTHCBSTHPO | |
| SCHEMBL4440753 | 0.73 | — | — | |
| SCHEMBL10390675 | 0.73 | — | — | |
| SCHEMBL13622944 | 0.73 | TSHR (0.30) | TSHRCTHCBSTHPO | |
| SCHEMBL16046345 | 0.73 | OR51E2 (0.40) | TSHRCTHCBSTHPO | |
| SCHEMBL28087733 | 0.73 | TSHR (0.43) | TSHRCTHCBSTHPOTHRB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2823886-B1 | Method of making hydroprocessing catalyst | ADVANCED REFINING TECHNOLOGIES LLC (US) | 2019-08-14 | — | — | EP | claimed |
| EP-1819705-A1 | METHOD FOR PREPARING HEXAHYDRO-8-HYDROXY-2,6-METHANO-2H-CHINOLIZIN-3(4H)-ONE ESTERS | Cilag Ltd. (CH) | 2007-08-22 | — | — | EP | disclosed |
| WO-2006056081-A1 | METHOD FOR PREPARING HEXAHYDRO-8-HYDROXY-2,6-METHANO-2H-CHINOLIZIN-3(4H)-ONE ESTERS | CILAG LTD. (CH) | 2006-06-01 | — | — | WO | disclosed |