Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.43 |
| ▸ | POLB | P06746 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.38 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
| ▸ | KIF11 | P52732 | 1/20 | 0.37 |
| ▸ | PKM | P14618 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5228389 | 0.88 | POLB (0.50) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL5227889 | 0.85 | POLB (0.46) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL5223851 | 0.84 | MAPT (0.45) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL5227374 | 0.84 | POLB (0.45) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL31009356 | 0.80 | MAPT (0.49) | MAPTMEN1KMT2AALDH1A1L3MBTL1 | |
| SCHEMBL8144288 | 0.78 | MAPT (0.51) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL24168437 | 0.77 | MAPT (0.54) | MAPTMEN1KMT2AKDM4EALDH1A1 | |
| SCHEMBL5224826 | 0.76 | MAPT (0.49) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL30539127 | 0.76 | MAPT (0.49) | MAPTPOLBMEN1KMT2AKDM4E | |
| SCHEMBL8152290 | 0.75 | MAPT (0.48) | MAPTMEN1KMT2AKDM4EALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1866287-B1 | SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES | BAYER IP GMBH (DE) | 2016-09-21 | — | — | EP | disclosed |
| EP-1866287-A2 | SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES | Bayer CropScience AG (DE) | 2007-12-19 | — | — | EP | disclosed |
| US-20060223709-A1 | Substituted pyrazolyloxyphenyl derivatives as herbicides | BAYER CROPSCIENCE GMBH (DE) | 2006-10-05 | — | — | US | disclosed |
| WO-2006103003-A2 | SUBSTITUTED PYRAZOLYL OXYPHENYL DERIVATIVES USED AS HERBICIDES | BAYER CROPSCIENCE AG (DE) | 2006-10-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20060223709-A1 | Substituted pyrazolyloxyphenyl derivatives as herbicides | DDT, CBR3, CYP1A1 | MAPT 3666/4885POLB 2713/4885MEN1 4204/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.