Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 7/20 | 0.52 |
| ▸ | PPARA | Q07869 | 6/20 | 0.52 |
| ▸ | MAPT | P10636 | 4/20 | 0.49 |
| ▸ | TP53 | P04637 | 4/20 | 0.49 |
| ▸ | POLB | P06746 | 3/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.45 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5224967 | 0.94 | PPARG (0.52) | PPARGPPARAMAPTTP53POLB | |
| SCHEMBL5223943 | 0.85 | PPARG (0.58) | PPARGPPARAMAPTFFAR1CYP2C9 | |
| SCHEMBL5228366 | 0.84 | PPARG (0.51) | PPARGPPARAMAPTTP53POLB | |
| SCHEMBL5231167 | 0.84 | PPARG (0.55) | PPARGPPARAMAPTTP53POLB | |
| SCHEMBL5227014 | 0.84 | PPARG (0.55) | PPARGPPARACYP2C9KCNH2 | |
| SCHEMBL5263579 | 0.83 | TP53 (0.53) | PPARGPPARAMAPTTP53POLB | |
| SCHEMBL5224964 | 0.79 | PPARG (0.59) | PPARGPPARAMAPTFFAR1CYP2C9 | |
| SCHEMBL5225370 | 0.77 | PPARG (0.52) | PPARGPPARAMAPTTP53POLB | |
| SCHEMBL5226750 | 0.77 | PPARG (0.58) | PPARGPPARAFFAR1CYP2C9KCNH2 | |
| SCHEMBL5227322 | 0.77 | PPARG (0.54) | PPARGPPARACYP2C9KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1778654-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | Crystalgenomics, Inc. (KR) | 2007-05-02 | — | — | EP | disclosed |
| WO-2006006832-A1 | SULFAMIDE DERIVATIVES AND PHARMACEUTICAL COMPOSITION FOR UPREGULATION OF LIPID METABOLISM COMPRISING SAME | CRYSTALGENOMICS, INC. (KR) | 2006-01-19 | — | — | WO | disclosed |