Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 15/20 | 0.69 |
| ▸ | CNR2 | P34972 | 12/20 | 0.69 |
| ▸ | NPC1 | O15118 | 2/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | BCHE | P06276 | 1/20 | 0.50 |
| ▸ | H4C1; H4C2; H4C3; H4C4; H4C5; H4C6; H4C8; H4C9; H4C11; H4C12; H4C13; H4C14; H4C15; H4C16 | P62805 | 1/20 | 0.46 |
| ▸ | EP300 | Q09472 | 1/20 | 0.46 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4191556 | 0.88 | CNR1 (0.68) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL4199022 | 0.85 | CNR1 (0.64) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL4203143 | 0.85 | CNR1 (0.70) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL4191297 | 0.85 | CNR1 (0.68) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL5163850 | 0.82 | CNR1 (1.00) | CNR1CNR2 | |
| SCHEMBL14410392 | 0.80 | CNR1 (0.66) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL5233179 | 0.80 | CNR1 (0.98) | CNR1CNR2 | |
| SCHEMBL5236434 | 0.79 | CNR1 (0.94) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL4194677 | 0.79 | CNR1 (0.73) | CNR1CNR2NPC1ALDH1A1BCHE | |
| SCHEMBL5158914 | 0.79 | CNR1 (1.00) | CNR1CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1756044-A1 | THERAPEUTIC COMPOUNDS | AstraZeneca AB (SE) | 2007-02-28 | — | — | EP | disclosed |
| WO-2005115972-A1 | THERAPEUTIC COMPOUNDS | ASTRAZENECA AB (SE) | 2005-12-08 | — | — | WO | disclosed |