Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNH2 | Q12809 | 15/20 | 0.72 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5222734 | 1.00 | KCNH2 (0.72) | KCNH2 | |
| SCHEMBL5222740 | 1.00 | KCNH2 (0.72) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6801439 | 0.99 | KCNH2 (0.71) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6801105 | 0.99 | KCNH2 (0.71) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6800805 | 0.99 | KCNH2 (0.71) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6801429 | 0.99 | KCNH2 (0.71) | KCNH2 | |
| Hydrochloric Acid SCHEMBL6801108 | 0.99 | KCNH2 (0.71) | KCNH2 | |
| SCHEMBL6144144 | 0.92 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL6144138 | 0.92 | KCNH2 (0.60) | KCNH2 | |
| SCHEMBL6798813 | 0.92 | KCNH2 (0.77) | KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1370550-B1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING SAME | NOVEXEL (FR) | 2007-05-23 | — | — | EP | disclosed |
| EP-1370550-A1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING SAME | Aventis Pharma S.A. (FR) | 2003-12-17 | — | — | EP | disclosed |
| WO-2002072572-A1 | QUINOLYL PROPYL PIPERIDINE DERIVATIVES, THE PREPARATION THEREOF AND COMPOSITIONS CONTAINING SAME | AVENTIS PHARMA S.A. (FR) | 2002-09-19 | — | — | WO | disclosed |