SCHEMBL5226029

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL6479442	0.84	NQO2 (0.53)	NQO2MTNR1AMTNR1BGSK3BCA12
	SCHEMBL5226683	0.84	GSK3B (0.40)	MTNR1BGSK3BALDH1A1HPGDL3MBTL1
	SCHEMBL5226482	0.78	NQO2 (0.58)	NQO2MTNR1AMTNR1BGSK3BCA12
	SCHEMBL3494354	0.77	NQO2 (0.56)	NQO2MTNR1AMTNR1BGSK3BCA12
	SCHEMBL19740390	0.77	NQO2 (0.56)	NQO2MTNR1AMTNR1BGSK3BCA12
	SCHEMBL12365259	0.75	GSK3B (0.61)	NQO2MTNR1AMTNR1BGSK3BALDH1A1
	SCHEMBL5228133	0.74	NQO2 (0.54)	NQO2MTNR1AMTNR1BGSK3BCA12
	SCHEMBL17858575	0.73	NQO2 (0.53)	NQO2MTNR1AMTNR1BGSK3BCA12
	SCHEMBL68516	0.72	CA1 (0.53)	NQO2CA12CA1CA2CA7
	SCHEMBL18439922	0.72	KDM4E (0.58)	CA12CA1CA2CA7XDH

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.