Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BCHE | P06276 | 1/20 | 0.60 |
| ▸ | CTSD | P07339 | 13/20 | 0.57 |
| ▸ | BACE1 | P56817 | 15/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5226037 | 1.00 | BCHE (0.60) | BCHECTSDBACE1 | |
| SCHEMBL5220622 | 0.93 | BCHE (0.58) | BCHECTSDBACE1 | |
| SCHEMBL5220617 | 0.93 | BCHE (0.58) | BCHECTSDBACE1 | |
| SCHEMBL3511029 | 0.92 | BCHE (0.69) | BCHECTSDBACE1 | |
| SCHEMBL255923 | 0.92 | BCHE (0.69) | BCHECTSDBACE1 | |
| SCHEMBL715242 | 0.92 | BCHE (0.69) | BCHECTSDBACE1 | |
| SCHEMBL3881697 | 0.89 | BCHE (0.56) | BCHECTSDBACE1 | |
| SCHEMBL3870494 | 0.89 | BCHE (0.56) | BCHECTSDBACE1 | |
| SCHEMBL3881693 | 0.89 | BCHE (0.56) | BCHECTSDBACE1 | |
| SCHEMBL3870491 | 0.89 | BCHE (0.56) | BCHECTSDBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1567488-B1 | HYDROXYETHYLAMINE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE | GLAXO GROUP LTD (GB) | 2007-02-21 | — | — | EP | disclosed |