⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1644470 | 1.00 | — | — | |
| SCHEMBL3221127 | 0.92 | TSHR (0.37) | — | |
| SCHEMBL28491985 | 0.89 | — | — | |
| SCHEMBL11665896 | 0.89 | TSHR (0.35) | — | |
| Ethylenediamine SCHEMBL11002045 | 0.85 | — | — | |
| SCHEMBL3047023 | 0.74 | — | — | |
| SCHEMBL317417 | 0.74 | — | — | |
| SCHEMBL3582419 | 0.72 | — | — | |
| SCHEMBL20336195 | 0.69 | — | — | |
| SCHEMBL1495223 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-11739122-B2 | Glycopeptide antibiotic compounds, methods for producing the same, and uses thereof | ACADEMIA SINICA (TW) | 2023-08-29 | — | — | US | disclosed |
| US-11007200-B2 | Cycloalkyl-diamines for the treatment of pain | MediSynergics, LLC (US) | 2021-05-18 | — | — | US | disclosed |
| US-20210060023-A1 | Cycloalkyl-Diamines for the Treatment of Inflammation | MediSynergics, LLC (US) | 2021-03-04 | — | — | US | disclosed |
| US-20210052594-A1 | Cycloalkyl-Diamines for the Treatment of Pain | MediSynergics, LLC (US) | 2021-02-25 | — | — | US | disclosed |
| US-20200291071-A1 | GLYCOPEPTIDE COMPOUNDS, METHODS FOR PRODUCING THE SAME, AND USES THEREOF | ACADEMIA SINICA (TW) | 2020-09-17 | — | — | US | disclosed |
| US-10351552-B2 | Bicyclic antiparasitic compounds | MediSynergies, LLC (US) | 2019-07-16 | — | — | US | disclosed |
| US-20190177304-A1 | Bicyclic Antiparasitic Compounds | MediSynergics, LLC (US) | 2019-06-13 | — | — | US | disclosed |
| WO-2017184765-A1 | KAPPA OPIOID RECEPTOR COMPOUNDS AND METHODS OF USING SAME | MediSynergics, LLC (US) | 2017-10-26 | — | — | WO | disclosed |
| US-9700563-B2 | Kappa opioid receptor compounds | MediSynergies, LLC (US) | 2017-07-11 | — | — | US | disclosed |
| US-9517232-B2 | Compounds for treatment of alzheimer's disease | Medi Synergics, LLC (US) | 2016-12-13 | — | — | US | disclosed |
| US-20060047114-A1 | Azabicyclic amine histamine-3 receptor antagonists | PFIZER INC | 2006-03-02 | — | — | US | disclosed |
| WO-2006011043-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-02-02 | — | — | WO | disclosed |
| US-20060019998-A1 | Histamine-3 receptor antagonist | PFIZER INC | 2006-01-26 | — | — | US | disclosed |
| US-20060014733-A1 | Histamine-3 agonists and antagonists | PFIZER INC | 2006-01-19 | — | — | US | disclosed |
| WO-2006000914-A1 | DIAZABICYCLIC HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. (US) | 2006-01-05 | — | — | WO | disclosed |
| US-20050282811-A1 | Diazabicyclic histamine-3 receptor antagonists | PFIZER INC | 2005-12-22 | — | — | US | disclosed |
| WO-2005105744-A1 | HISTAMINE-3 RECEPTOR ANTAGONISTS | PFIZER PRODUCTS INC. | 2005-11-10 | — | — | WO | disclosed |
| US-20050245543-A1 | Histamine-3 receptor antagonists | PFIZER INC | 2005-11-03 | — | — | US | disclosed |
| WO-2005080361-A1 | HISTAMINE-3 RECEPTOR MODULATORS | PFIZER PRODUCTS INC. (US) | 2005-09-01 | — | — | WO | disclosed |
| US-20050171181-A1 | 3-Benzyloxymethyl-1-(4-pyrrolidin-1-ylmethyl-phenyl)-cyclobutanol for example; treating allergies and mood disorders; use in combination with a histamine H1 antagonist or a neurotransmitter re-uptake blocker | PFIZER INC | 2005-08-04 | — | — | US | disclosed |